منابع مشابه
A controlled trial of meprobamate in anxious out-patients.
Meprobamate was first synthesized by Ludwig and Piech in 1951. Its pharmacological properties have been studied by Berger, who described it as an interneuronal blocking agent related to mephenesin (Berger, 1954; Berger, Hendley, Ludwig, and Lynes, 1956). He noted that when it was administered to monkeys they became more manageable and did not demonstrate fear when handled. Early reports of its ...
متن کاملA controlled clinical trial of meprobamate in the management of difficult and destructive female mental defectives.
MEPROBAMATE is the shortened name of 2-Methyl-2-n-Propyl-l,3 propanediol dicarbamate, which is also known as Miltown or Equanil. Previously published reports (1—5)on clinical trials of this drug have concerned its effect on patients suffering from neurotic and psychotic disorders. As far as we are aware no reports have been published of its effects on mentally defective patients. The clinical...
متن کاملMeprobamate in tetanus.
T H E value of oral meprobamate (syn. Equanil, Miltown, Mepavlon) has been for some months 1st day after admission. In the morning his breathing was rather laboured and mucus collected in his throat. Later he managed investigated in this hospital group, as a compoto swallow this and his breathing improved. He was nent of the premedication for children. An interesting publication has appeared re...
متن کاملThe effects of meprobamate and pentobarbitone sodium on sleep and motility during sleep: a controlled trial with psychiatric patients.
Meprobamate (2-methyl-2-n-propyl-1, 3-propanediol dicarbamate) was synthesized by Ludwig and Piech (1951). It is an interneuronal blocking agent capable of producing muscular relaxation without affecting respiration or other vital activities (Berger, 1954). The drug produces restful sleep and generalized muscular relaxation (Borrus, 1955). It was decided to test its effect, compared with that o...
متن کاملReversible agranulocytosis due to meprobamate.
A 52 year old man admitted to hospital in a toxic state, was found to have agranulocytosis, which recovered when an analgesic containing meprobamate was stopped. The patient was known to have had similar symptoms 9 months previously when the drug was first used, thereby demonstrating an idiosyncratic reaction to meprobamate.
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ژورنال
عنوان ژورنال: BMJ
سال: 1956
ISSN: 0959-8138,1468-5833
DOI: 10.1136/bmj.2.5003.1206